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GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa); inhibits ATX-II-induced late I(Na) in ventricular myocytes and isolated hearts with IC(50) values of 0.13 and 0.21 uM, respectively.
| In vitro | DMSO | 38 mg/mL (109.44 mM) | |
| Water | Insoluble | ||
| Ethanol | 39 mg/mL (112.32 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.8 mL | 144 mL | 288 mL |
| 0.5 mM | 5.76 mL | 28.8 mL | 57.6 mL |
| 1 mM | 2.88 mL | 14.4 mL | 28.8 mL |
| 5 mM | 0.58 mL | 2.88 mL | 5.76 mL |
*The above data is based on the productmolecular weight 347.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14361 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1262618-39-2 |
| Formula | C14H7F6N3O |
| M. Wt | 347.22 |
| Purity | >98% |
| Synonyms | GS-967, GS 967 |
| SMILES | FC(F)(F)C1=NN=C2C=CC(C3=CC=C(OC(F)(F)F)C=C3)=CN21 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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