GSK-1520489A

Catalog No.: A57240
PKMYT1 Inhibitor
GSK-1520489A is a selective inhibitor of PKMYT1, an active protein kinase involved in cell cycle regulation. It exhibits an IC50 of 115 nM and a Ki value of 10.94 nM, demonstrating significant potency in inhibition. This compound is useful for exploring the role of PKMYT1 in tumorigenesis and cell proliferation, making it a valuable tool in cancer research and therapeutic discovery.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$100.00
In stock
10mg
$165.00
In stock
25mg
$290.00
In stock
50mg
$385.00
In stock
100mg
$530.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGSK-1520489A is a selective inhibitor of PKMYT1, an active protein kinase involved in cell cycle regulation. It exhibits an IC50 of 115 nM and a Ki value of 10.94 nM, demonstrating significant potency in inhibition. This compound is useful for exploring the role of PKMYT1 in tumorigenesis and cell proliferation, making it a valuable tool in cancer research and therapeutic discovery.
Product Information
Catalog NumA57240
FormulaC21H23N5O3S
Molecular Weight425.50
CAS Number1042433-41-9
SMILESO=C(C1=C(NC2=NC(NC3=CC=CC(CS(=O)(C)=O)=C3)=NC=C2C)C=CC=C1)NC
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