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GSK-2033 is a potent cell-active LXR antagonist (pIC50 = 7.5). It enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells and is cell permeable.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.9 mL | 84.51 mL | 169.02 mL |
| 0.5 mM | 3.38 mL | 16.9 mL | 33.8 mL |
| 1 mM | 1.69 mL | 8.45 mL | 16.9 mL |
| 5 mM | 0.34 mL | 1.69 mL | 3.38 mL |
*The above data is based on the productmolecular weight 591.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17017 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1221277-90-2 |
| Formula | C29H28F3NO5S2 |
| M. Wt | 591.66 |
| Purity | >98% |
| Synonyms | GSK2033, GSK 2033 |
| SMILES | O=S(C1=C(C)C=C(C)C=C1C)(N(CC2=CC=C(C3=CC=CC(S(=O)(C)=O)=C3)C=C2)CC4=CC=C(C(F)(F)F)O4)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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