GSK-2033

Catalog No.: A17017

LXR antagonist

GSK-2033

GSK-2033 Chemical Structure

CAS NO. 1221277-90-2

GSK-2033 is a potent cell-active LXR antagonist (pIC50 = 7.5). It enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells and is cell permeable.

Availability: In stock

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5 mg

Regular Price: $120.00

Special Price $96.00

10 mg

Regular Price: $195.00

Special Price $156.00

50 mg

Regular Price: $680.00

Special Price $544.00

100 mg

Regular Price: $1,180.00

Special Price $944.00

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Biological Activity

GSK-2033 is a potent cell-active LXR antagonist (pIC50 = 7.5). It enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells and is cell permeable.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.9 mL 84.51 mL 169.02 mL
0.5 mM 3.38 mL 16.9 mL 33.8 mL
1 mM 1.69 mL 8.45 mL 16.9 mL
5 mM 0.34 mL 1.69 mL 3.38 mL

*The above data is based on the productmolecular weight 591.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17017
Actions Antagonist
CAS No. 1221277-90-2
Formula C29H28F3NO5S2
M. Wt 591.66
Purity >98%
Synonyms GSK2033, GSK 2033
SMILES O=S(C1=C(C)C=C(C)C=C1C)(N(CC2=CC=C(C3=CC=CC(S(=O)(C)=O)=C3)C=C2)CC4=CC=C(C(F)(F)F)O4)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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