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GSK 269962

ROCK inhibotor

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Catalog No. A12348

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK 269962 5mg A12348-5
GSK 269962 10mg A12348-10
GSK 269962 25mg A12348-25
GSK 269962 50mg A12348-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK 269962 is a potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively).

GSK 269962

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Publications citing Adooq Products
GSK 269962 Citations (1)
  • Praneeth Siripurapu, .et al. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration, J Biol Chem, 2017, Oct 20; 292(42): 17482-17495 PMID: 28864771

Chemical Information

Catalog Num A12348
Actions Inhibitor
M. Wt 570.6
Formula C29H30N8O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 850664-21-0
Synonyms GSK269962,GSK-269962, GSK269962A, GSK-269962A

Biological Activity

GSK 269962 is a potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.53 mL 87.63 mL 175.25mL
0.5 mM 3.51 mL 17.53 mL 35.05 mL
1 mM 1.75 mL 8.76 mL 17.53 mL
5 mM 0.35 mL 1.75 mL 3.51 mL

*The above data is based on the productmolecular weight 570.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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