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Publications citing Adooq Products
GSK 269962 Citations (1)
- Praneeth Siripurapu,et al. Two independent but synchronized G汕污 subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration, J Biol Chem, 2017, Oct 20; 292(42): 17482-17495 28864771
Chemical Information
| Catalog Num | A12348 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 570.6 |
| Formula | C29H30N8O5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 850664-21-0 |
| Synonyms | GSK269962,GSK-269962, GSK269962A, GSK-269962A |
| SMILES code | CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6 |
| Chemical Name | N-[3-[[2-(4-Amino-1,2,5-oxadiazol-3?-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phe?nyl]-4-[2-(4-morpholinyl)ethoxy]benzamide |
Description |
GSK 269962 is a potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.53 mL | 87.63 mL | 175.25mL |
| 0.5 mM | 3.51 mL | 17.53 mL | 35.05 mL |
| 1 mM | 1.75 mL | 8.76 mL | 17.53 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.51 mL |
*The above data is based on the productmolecular weight 570.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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