Fig. 1 · Structure
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GSK-2793660
CTSC Inhibitor
GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). This compound demonstrates significant potential for investigating the role of CTSC in bronchiectasis and related conditions. Its efficacy as a CTSC inhibitor makes it a valuable tool for exploring therapeutic approaches aimed at modulating inflammation and tissue remodeling in respiratory diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1613458-78-8 |
| Applications | CTSC Inhibitor |
| Formula | C20H28ClN3O3 |
| Molecular Weight | 393.91 |
| SMILES | NC1(C(N[C@@H](CC)/C=C/C(N2CCC3=C2C=CC=C3)=O)=O)CCOCC1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.