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GSK-4381562
Anti-PVRIG (GSK4381562) is a human monoclonal antibody of the immunoglobulin G1 (IgG1) class, targeting the poliovirus receptor-related immunoglobulin domain-containing protein (PVRIG, also known as CD112R). This antibody is designed to modulate immune response through its inhibitory effects on the PVRIG pathway, which is implicated in immune checkpoint regulation. The interaction between Anti-PVRIG and its target has the potential to enhance antitumor immune activity by alleviating immune suppression in the tumor microenvironment, thereby offering therapeutic benefits in oncology research and treatment.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Applications | PVRIG Antibody |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.