GSK-843

Catalog No.: A18526

RIPK3 inhibitor

GSK-843

GSK-843 Chemical Structure

CAS NO. 1601496-05-2

GSK-843 (GSK'843) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM.

Availability: In stock

Package Price Qty
5 mg
$300.00
10 mg
$550.00
50 mg
$1,800.00
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Biological Activity

GSK-843 (GSK'843) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.49 mL 132.45 mL 264.91 mL
0.5 mM 5.3 mL 26.49 mL 52.98 mL
1 mM 2.65 mL 13.25 mL 26.49 mL
5 mM 0.53 mL 2.65 mL 5.3 mL

*The above data is based on the productmolecular weight 377.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18526
Actions Inhibitor
M. Wt 377.49
Formula C19H15N5S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1601496-05-2
Synonyms GSK843, GSK 843
SMILES NC1=NC=C(C2=CC(C)=NN2C)C3=C1C(C4=CC=C(SC=N5)C5=C4)=CS3

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