GSK-923295

Catalog No.: A11435

CENP-E inhibitor

GSK-923295

GSK-923295 Chemical Structure

CAS NO. 1088965-37-0

GSK-923295, is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E, (CENP-E).

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5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $170.00

Special Price $136.00

25 mg

Regular Price: $340.00

Special Price $272.00

50 mg

Regular Price: $620.00

Special Price $496.00

10mM * 1mL in DMSO

Regular Price: $189.00

Special Price $151.20

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Biological Activity

GSK-923295, is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E, (CENP-E).
Targets
CENP-E
3.2 nM(Ki)
In vitro DMSO 90 mg/mL (151.99 mM)
Water Insoluble
Ethanol 90 mg/mL (151.99 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.89 mL 84.44 mL 168.88 mL
0.5 mM 3.38 mL 16.89 mL 33.78 mL
1 mM 1.69 mL 8.44 mL 16.89 mL
5 mM 0.34 mL 1.69 mL 3.38 mL

*The above data is based on the productmolecular weight 592.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11435
Actions Inhibitor
CAS No. 1088965-37-0
Formula C32H38ClN5O4
M. Wt 592.13
Purity >98%
Synonyms GSK923295, GSK 923295
SMILES C[[email protected]@H](C1=CC=CN2C1=NC(=C2)C3=CC=C(C=C3)C[[email protected]@H](CNC(=O)CN(C)C)NC(=O)C4=CC(=C(C=C4)OC(C)C)Cl)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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