Fig. 1 · Structure
Documents & Downloads
GSK-F1
PI4KA Inhibitor
GSK-F1 is a potent inhibitor of phosphoinositide 4-kinase alpha (PI4KA), exhibiting a pIC50 value of 8.0 against PI4KA, along with significant activity against other phosphoinositide kinases. This compound is primarily utilized in research related to hepatitis C virus (HCV) infection, providing insights into the role of PI4KA in viral replication and pathogenesis. GSK-F1 serves as a valuable tool for understanding PI4K pathway modulation and its implications in viral infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1402345-92-9 |
| Applications | PI4KA Inhibitor |
| Formula | C27H18F5N5O4S |
| Molecular Weight | 603.52 |
| SMILES | O=S(C1=CC(C2=CC3=C(N=C(N)N(C4=CC=CC=C4C(F)(F)F)C3=O)C=C2)=CN=C1OC)(NC5=CC=C(F)C=C5F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.