Fig. 1 · Structure
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GSK-J5
Schistosome Inhibitor
GSK-J5 is a potent inhibitor targeting Schistosoma species. This compound demonstrates significant biological activity by increasing the mortality of schistosomula and adult worms, as well as enhancing the motility of adult worms and affecting egg oviposition in a dose- and time-dependent manner. GSK-J5 is useful for research applications aimed at understanding schistosomiasis and developing therapeutic strategies against parasitic infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1394854-51-3 |
| Applications | Schistosome Inhibitor |
| Formula | C24H27N5O2 |
| Molecular Weight | 417.50 |
| SMILES | O=C(OCC)CCNC1=NC(C2=CC=CN=C2)=NC(N3CCC(C=CC=C4)=C4CC3)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.