GSK1278863 (Daprodustat)

Catalog No.: A12671

HIF-prolyl hydroxylase Inhibitor

GSK1278863 (Daprodustat)

GSK1278863 (Daprodustat) Chemical Structure

CAS NO. 960539-70-2

GSK1278863 is a novel HIF-prolyl hydroxylase inhibitor.

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Biological Activity

GSK1278863 is a novel HIF-prolyl hydroxylase inhibitor.
In vitro DMSO Warmed: 9 mg/mL (22.87 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.42 mL 127.08 mL 254.17 mL
0.5 mM 5.08 mL 25.42 mL 50.83 mL
1 mM 2.54 mL 12.71 mL 25.42 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12671
Actions Inhibitor
CAS No. 960539-70-2
Formula C19H27N3O6
M. Wt 393.44
Solubility DMSO
Purity >98%
Synonyms Daprodustat, GSK 1278863, GSK-1278863

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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