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GSK1331268

mGluR2 Agonist

GSK1331268 is a selective, orally active agonist of the metabotropic glutamate receptor 2 (mGluR2) with a pEC50 of 6.9. This compound demonstrates effective penetration of the blood-brain barrier, allowing for modulation of glutamate signaling within the central nervous system. GSK1331268 is suitable for research applications focused on neurodegenerative and neuropsychiatric disorders, providing valuable insight into potential therapeutic pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1207197-70-3
Applications	mGluR2 Agonist
Formula	C₁₇H₁₉ClN₆
Molecular Weight	342.83
SMILES	ClC1=CN=C(N2CCN(CC2)CC3=NC4=C(N3C)C=CC=C4)N=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.