Fig. 1 · Structure
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GSK1790627
Trametinib Metabolite
GSK1790627 is the N-deacetylated metabolite of Trametinib, a potent and selective MEK inhibitor. This compound exhibits biological activities that include the activation of autophagy and the induction of apoptosis in tumor cells. GSK1790627 is instrumental in research focused on cancer treatment and the mechanistic understanding of MEK pathway modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 871701-87-0 |
| Applications | Trametinib Metabolite |
| Formula | C24H21FIN5O3 |
| Molecular Weight | 573.36 |
| SMILES | O=C1N(C2=CC=CC(N)=C2)C(C(C(N1C3CC3)=O)=C(NC4=CC=C(I)C=C4F)N5C)=C(C)C5=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.