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Biological Activity
GSK189254A (GSK189254) is a novel, potent and selective histamine H3 receptor antagonist with pKi values of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.45 mL | 142.27 mL | 284.54 mL |
| 0.5 mM | 5.69 mL | 28.45 mL | 56.91 mL |
| 1 mM | 2.85 mL | 14.23 mL | 28.45 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
*The above data is based on the productmolecular weight 351.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A22005 |
|---|---|
| Actions | Antagonist |
| CAS No. | 720690-73-3 |
| Formula | C21H25N3O2 |
| M. Wt | 351.44 |
| Purity | >98% |
| Synonyms | GSK189254, GSK 189254, GSK-189254 |
| SMILES | O=C(NC)C(C=N1)=CC=C1OC2=CC(CC3)=C(C=C2)CCN3C4CCC4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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