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Biological Activity
GSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist, which inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96±0.11.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.21 mL | 91.06 mL | 182.13 mL |
| 0.5 mM | 3.64 mL | 18.21 mL | 36.43 mL |
| 1 mM | 1.82 mL | 9.11 mL | 18.21 mL |
| 5 mM | 0.36 mL | 1.82 mL | 3.64 mL |
*The above data is based on the productmolecular weight 549.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12175 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1240516-71-5 |
| Formula | C24H25ClN4O5S2 |
| M. Wt | 549.06 |
| Purity | >98% |
| Synonyms | GSK 2239633A, GSK-2239633A |
| SMILES | CC(C)(O)C(NCC1=CC=CC(CN2N=C(NS(=O)(C3=CC=C(Cl)S3)=O)C4=C2C=CC=C4OC)=C1)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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