Fig. 1 · Structure
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GSK329
TNNI3K Inhibitor
GSK329 is a selective inhibitor of the cardiac-specific kinase TNNI3K. It demonstrates significant cardioprotective effects in models of ischemia/reperfusion injury, making it a valuable tool for research into cardiac protection mechanisms. Its potency and specificity offer potential applications in studying cardiovascular diseases and developing therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1268490-12-5 |
| Applications | TNNI3K Inhibitor |
| Formula | C19H14Cl2F3N5O2 |
| Molecular Weight | 472.25 |
| SMILES | O=C(NC1=CC(Cl)=C(C(Cl)=C1)OC2=NC=NC(NC)=C2)NC3=CC=CC(C(F)(F)F)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.