GSK467

Catalog No.: A18807

KDM5B (JARID1B or PLU1) inhibitor

GSK467

GSK467 Chemical Structure

CAS NO. 1628332-52-4

GSK467 is a potent and selective inhibitor of KDM5 (also known as JARID1) with a Ki of 10 nM, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members. GSK467 exploits unique binding modes.

Availability: In stock

Package Price Qty
5 mg
$200.00
10 mg
$300.00
50 mg
$980.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GSK467 is a potent and selective inhibitor of KDM5 (also known as JARID1) with a Ki of 10 nM, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members. GSK467 exploits unique binding modes.
In vitro DMSO 7 mg/mL (21.92 mM)
Water <1 mg/mL
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.32 mL 156.58 mL 313.17 mL
0.5 mM 6.26 mL 31.32 mL 62.63 mL
1 mM 3.13 mL 15.66 mL 31.32 mL
5 mM 0.63 mL 3.13 mL 6.26 mL

*The above data is based on the productmolecular weight 319.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18807
Actions Inhibitor
CAS No. 1628332-52-4
Formula C17H13N5O2
M. Wt 319.32
Purity >98%
Synonyms GSK467; GSK-467; GSK 467;
SMILES O=C1C2=C(C=NC=C2)N=C(OC3=CN(CC4=CC=CC=C4)N=C3)N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy GSK467 | GSK467 Supplier | purchase | cost | manufacturer | order | distributor | buy 1628332-52-4| 1628332-52-4 Supplier | purchase 1628332-52-4 | 1628332-52-4 cost | 1628332-52-4 manufacturer | order 1628332-52-4 | 1628332-52-4 distributor
Rewards