GSK547

Catalog No.: A19073

RIP1 inhibitor

GSK547

GSK547 Chemical Structure

CAS NO. 2226735-55-1

GSK547 (GSK-547) is a highly selective and potent inhibitor of receptor-interacting serine/threonine protein kinase 1 (RIP1), inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.

Availability: In stock

Package Price Qty
5 mg
$280.00
10 mg
$480.00
50 mg
$1,420.00
100 mg
$2,400.00
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Biological Activity

GSK547 (GSK-547) is a highly selective and potent inhibitor of receptor-interacting serine/threonine protein kinase 1 (RIP1), inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.
In vitro DMSO 26 mg/mL (65.59 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.23 mL 126.14 mL 252.28 mL
0.5 mM 5.05 mL 25.23 mL 50.46 mL
1 mM 2.52 mL 12.61 mL 25.23 mL
5 mM 0.5 mL 2.52 mL 5.05 mL

*The above data is based on the productmolecular weight 396.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19073
Actions Inhibitor
CAS No. 2226735-55-1
Formula C20H18F2N6O
M. Wt 396.39
Purity >98%
Synonyms GSK-547, GSK547
SMILES N#CC1=NC=NC(N2CCC(C(N3N=CC[[email protected]]3C4=CC(F)=CC(F)=C4)=O)CC2)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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