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$0.00 Biological Activity
GSK591 is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 11 nM.
Targets
| PRMT5 | ||||
| 4nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.28 mL | 131.41 mL | 262.83 mL |
| 0.5 mM | 5.26 mL | 26.28 mL | 52.57 mL |
| 1 mM | 2.63 mL | 13.14 mL | 26.28 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
*The above data is based on the productmolecular weight 380.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A14374 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 380.48 |
| Formula | C22H28N4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1616391-87-7 |
| Synonyms | EPZ015866,GSK3203591 |
| SMILES | O=C(NC[[email protected]](O)CN1CCC(C=CC=C2)=C2C1)C3=CC(NC4CCC4)=NC=C3 |
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