Fig. 1 · Structure

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(-)-GSK598809 ((1S,5R)-GSK598809)

Dopamine Receptor Antagonist

(-)-GSK598809 is a selective antagonist of the dopamine D3 receptor (DRD3). This compound exhibits potent inhibition of DRD3 activity, making it a valuable tool for research into neuropsychiatric disorders and addiction. Its specificity for DRD3 allows for detailed investigations into dopamine-related signaling pathways and their implications for various therapeutic areas.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 863680-46-0
Applications Dopamine Receptor Antagonist
Formula C22H23F4N5OS
Molecular Weight 481.51
Synonyms (1S,5R)-GSK598809
SMILES
CC1=C(C2=NN=C(SCCCN3C[C@@]4(C5=CC=C(C(F)(F)F)C=C5F)C[C@@]4([H])C3)N2C)OC=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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