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GSK6853

BRPF1 bromodomain inhibitor

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Catalog No. A16330

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK6853 5mg A16330-5
€76.00
GSK6853 10mg A16330-10
€133.00
GSK6853 50mg A16330-50
€399.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK6853 is a potent and selective inhibitor of the BRPF1 bromodomain. shows excellent BRPF1 potency (pKd 9.5) and greater than 1600-fold selectivity over all other bromodomains tested.

GSK6853

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Chemical Information

Catalog Num A16330
Actions Inhibitor
M. Wt 409.48
Formula C22H27N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1910124-24-1
Synonyms GSK-6853, GSK 6853
SMILES O=C(NC1=C(N2[[email protected]](C)CNCC2)C=C(N3C)C(N(C)C3=O)=C1)C4=CC=CC=C4OC

Biological Activity

Description
GSK6853 is a potent and selective inhibitor of the BRPF1 bromodomain. shows excellent BRPF1 potency (pKd 9.5) and greater than 1600-fold selectivity over all other bromodomains tested.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.42 mL 122.11 mL 244.21mL
0.5 mM 4.88 mL 24.42 mL 48.84 mL
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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