GSK840 is a highly potent inhibitor of receptor-interacting protein kinase 3 (RIPK3), exhibiting an IC50 of 0.9 nM for binding to the RIP3 kinase domain and an IC50 of 0.3 nM for inhibiting its kinase activity. This compound provides a valuable tool for studying RIPK3-mediated pathways and their role in programmed cell death and inflammation. GSK840 is applicable in research focused on neurodegenerative diseases, cancer, and immune responses.
GSK840 is a highly potent inhibitor of receptor-interacting protein kinase 3 (RIPK3), exhibiting an IC50 of 0.9 nM for binding to the RIP3 kinase domain and an IC50 of 0.3 nM for inhibiting its kinase activity. This compound provides a valuable tool for studying RIPK3-mediated pathways and their role in programmed cell death and inflammation. GSK840 is applicable in research focused on neurodegenerative diseases, cancer, and immune responses.
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