Fig. 1 · Structure
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GSK854
TNNI3K Inhibitor
GSK854 is a potent inhibitor of Troponin I-Interacting Kinase (TNNI3K), targeting an essential regulator of cardiac function. This compound has been utilized in in vivo studies to investigate the role of TNNI3K in heart failure, highlighting its potential as a lead in the development of novel cardiac therapeutics. GSK854's ability to modulate TNNI3K activity makes it a valuable tool for research into cardiac diseases and associated pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1316059-00-3 |
| Applications | TNNI3K Inhibitor |
| Formula | C18H19ClN6O4S2 |
| Molecular Weight | 482.96 |
| SMILES | O=S(C1=CC=C(C(NC2=NC=NC(NC3=NC=C(C=C3)Cl)=C2)=C1)S(=O)(CC)=O)(NC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.