GSK866

Catalog No.: A64730
Glucocorticoid Receptor Agonist
GSK866, also known as (S)-GSK47866A, is a selective agonist of the glucocorticoid receptor, exhibiting an IC50 of 4.6 nM. This compound is utilized in research to explore the biological effects mediated by glucocorticoid receptor activation, including anti-inflammatory responses and cell signaling pathways. Its potency makes GSK866 a valuable tool in studies aimed at understanding the therapeutic potential of glucocorticoids in various diseases.
Grouped product items
Size Price Stock Qty
5mg
$510.00
In stock
10mg
$830.00
In stock
25mg
$1,665.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGSK866, also known as (S)-GSK47866A, is a selective agonist of the glucocorticoid receptor, exhibiting an IC50 of 4.6 nM. This compound is utilized in research to explore the biological effects mediated by glucocorticoid receptor activation, including anti-inflammatory responses and cell signaling pathways. Its potency makes GSK866 a valuable tool in studies aimed at understanding the therapeutic potential of glucocorticoids in various diseases.
Product Information
Catalog NumA64730
FormulaC23H21Cl2F4N5O3
Molecular Weight562.34
CAS Number1991970-93-4
SMILESNC1=C(C(NC[C@](C(F)(F)F)(O)CN(CC)C(C2=C(C=CC=C2Cl)Cl)=O)=O)C=NN1C3=CC=C(C=C3)F
Synonyms(S)-GSK47866A
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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