Fig. 1 · Structure
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GSK951A
THPP Analogue
GSK951A is a THPP analogue that specifically inhibits mycolic acid biosynthesis. This compound demonstrates significant potency in various culture systems while exhibiting effective in vivo activity. Notably, GSK951A is characterized by its low cytotoxicity, making it a valuable tool for studying bacterial infections and mycobacterial pathogenicity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1403602-33-4 |
| Applications | THPP Analogue |
| Formula | C24H23F3N4O3 |
| Molecular Weight | 472.46 |
| SMILES | O=C(C1=C2N(N=C1)[C@@H](C[C@@](C3=CC=C(C=C3)CC)([H])N2)C(F)(F)F)NCC4=CC=C(OCO5)C5=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.