Documents & Downloads

GSPT1 degrader-10

GSPT1 Molecular Glue Degrader

GSPT1 degrader-10 is a cereblon-based molecular glue degrader that selectively targets and degrades GSPT1, achieving over 95% degradation. This compound has demonstrated potent inhibition of cell viability in HL-60 cells, with an IC50 of 10 nM. GSPT1 degrader-10 is valuable for research applications involving the modulation of GSPT1-related pathways and mechanisms in cellular studies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3024909-61-0
Applications	GSPT1 Molecular Glue Degrader
Formula	C₃₈H₃₈ClN₇O₅
Molecular Weight	708.21
SMILES	O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC(CC4)CN5C(N(CCC5)C6=CC(C7=C(Cl)C8=C(NC=C8CC)N=C7)=CC=C6)=O)C=C3C2=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.