Fig. 1 · Structure

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GSPT1 degrader-15

GSPT1 Molecular Gel Degrader

GSPT1 degrader-15 is a selective degrader targeting GSPT1, with a DC50 of 154 nM. This compound demonstrates substantial anti-proliferative effects on leukemia and lymphoma cells, while exhibiting minimal impact on the expression of other proteins. GSPT1 degrader-15 is suitable for research applications focused on leukemia and lymphoma, providing a valuable tool for investigating GSPT1-related pathways in cancer biology.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 3060504-66-4
Applications GSPT1 Molecular Gel Degrader
Formula C36H29N5O7S
Molecular Weight 675.71
SMILES
O=C(NC1=O)CCC1N(C(C2=CC=C3)=O)CC2=C3C4=CC=CC=C4OCC(N/N=C/C5=CN(S(C6=CC=CC=C6)(=O)=O)C7=C5C=CC=C7)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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