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GSPT1 degrader-2

GSPT1 Degrader

GSPT1 degrader-2 is a potent molecular glue degrader that targets GSPT1, demonstrating a DC50 of less than 30 nM. This compound exhibits significant antitumor activity, making it a valuable tool for cancer research. Its ability to selectively degrade GSPT1 offers insights into the mechanisms of tumor biology and therapeutic potential in an array of malignancies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2803879-60-7
Applications	GSPT1 Degrader
Formula	C₂₂H₂₀ClN₃O₅
Molecular Weight	441.86
SMILES	O=C(NC(CC1)=O)C1N2CC(C=CC(COC(NC3=CC(Cl)=C(C)C=C3)=O)=C4)=C4C2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.