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GSPT1 degrader-5

GSPT1 Degrader

GSPT1 Degrader-5 is a potent GSPT1-targeting molecule that functions as a proteolysis-targeting chimera (PROTAC) with a DC50 of 144 nM. This compound selectively degrades GSPT1, a crucial regulatory protein involved in translation termination and mRNA surveillance. GSPT1 Degrader-5 is valuable for research applications focused on understanding the role of GSPT1 in various cellular processes and its implications in disease models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3034764-38-7
Applications	GSPT1 Degrader
Formula	C₂₄H₁₈F₄N₄O₆
Molecular Weight	534.42
SMILES	O=C(OCC1=CC=C2C(C=C(CN3C4C(NC(CC4)=O)=O)N2C3=O)=C1)NC5=C(F)C=CC(OC(F)(F)F)=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.