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GSPT1 degrader-6

GSPT1 Degrader

GSPT1 Degrader-6 is a selective degrader targeting GSPT1 through a unique mechanism that promotes the recruitment of the ubiquitin-proteasome system for degradation. With a DC50 value of 13 nM, it demonstrates potent biological activity in modulating GSPT1 levels. This compound is primarily used in research applications focusing on protein homeostasis, cellular stress responses, and the therapeutic modulation of GSPT1-related pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3034764-41-2
Applications	GSPT1 Degrader
Formula	C₂₄H₂₂ClN₅O₅
Molecular Weight	495.91
SMILES	ClC1=CC(NC(OCC2=CC=C3C(C=C(CN4C5C(NC(CC5)=O)=O)N3C4=O)=C2)=O)=CC=C1NC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.