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GSPT1 degrader-7

GSPT1 Molecular Glue Degrader

GSPT1 degrader-7 is a molecular glue degrader that targets GSPT1, exhibiting potent biological activity with an EC50 of 0.2 nM in DF15 multiple myeloma cells. This compound facilitates the selective degradation of GSPT1, making it a valuable tool for investigating the mechanisms of cancer progression and therapeutic responses. GSPT1 degrader-7 is applicable in cancer research, particularly in studies focused on multiple myeloma.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3082942-43-3
Applications	GSPT1 Molecular Glue Degrader
Formula	C₂₈H₂₄F₂N₄O₅
Molecular Weight	534.51
SMILES	O=C(NC1=CC=C(C=C1F)OCC2=CC=CC=C2)NCC3=CC=C4C(N(CC4=C3F)C5CCC(NC5=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.