Fig. 1 · Structure
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GST-FH.4
GST-FH Compound
GST-FH.4 is an inhibitor targeting glutathione S-transferase (GST), a critical enzyme involved in detoxification processes. This compound effectively inhibits GST activity, with an IC50 value of 24.38 μM, thereby reducing the frequency of false positive interactions observed between GST and glutathione (GSH). GST-FH.4 is a valuable tool for researchers studying enzymatic pathways and the dynamics of protein interactions in cellular processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1358386-87-4 |
| Applications | GST-FH Compound |
| Formula | C20H20N6O3S |
| Molecular Weight | 424.48 |
| SMILES | COC1=C(C=CC=C1)N2N=NC(C3=NSC(NC4=CC=C(C(OC)=C4)OC)=N3)=C2C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.