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GSTO1-IN-4

GSTO1-1 Inhibitor

GSTO1-IN-4 is a selective inhibitor of GSTO1-1, exhibiting potent activity with an IC50 of 0.04 μM and a KI of 0.16 μM. This compound demonstrates minimal inhibition of GSTO2-2, GSTA1-1, and GSTP1-1, making it a valuable tool for specific targeting. GSTO1-IN-4 effectively reduces inflammation in murine models and notably enhances the cytotoxic effects of Cisplatin. Its applications extend to inflammation research and the study of breast cancer.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	158890-33-6
Applications	GSTO1-1 Inhibitor
Formula	C₁₆H₂₂ClNO
Molecular Weight	279.80
SMILES	O=C(N1CCC(CC1)CCCC2=CC=CC=C2)CCl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.