Fig. 1 · Structure
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GTSE1-IN-1
GTSE1 Inhibitor
GTSE1-IN-1 is a selective inhibitor of GTSE1, functioning primarily by suppressing its transcription and protein expression levels. This compound effectively inhibits cancer cell proliferation by inducing cell cycle arrest and promoting cellular senescence in the presence of persistent DNA damage. GTSE1-IN-1 is suitable for research applications related to various cancers, including colon and lung cancer, providing insights into the mechanisms of tumorigenesis and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3002034-34-3 |
| Applications | GTSE1 Inhibitor |
| Formula | C21H24FN7 |
| Molecular Weight | 393.46 |
| SMILES | FC1=CN=C(NC2=CC=C(N3CCN(C)CC3)C=C2)N=C1NC4=CC=C(N)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.