Fig. 1 · Structure
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Guaiol
Bioactive Sesquiterpene Alcohol
Guaiol is a bioactive sesquiterpene alcohol known for its diverse biological activities, including anti-proliferative, anti-inflammatory, and diuretic effects. It induces apoptosis in non-small cell lung cancer cells by modulating the stability of RAD51 through autophagy mechanisms. Additionally, guaiol exhibits insecticidal properties and directly targets parasites, inhibiting their growth by disrupting the kinetoplast and plasma membrane, with an IC50 of 0.01 µg/mL against amastigotes. This compound is applicable in research focused on cancer, infectious diseases, cardiovascular health, and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 489-86-1 |
| Applications | Bioactive Sesquiterpene Alcohol |
| Formula | C15H26O |
| Molecular Weight | 222.37 |
| Synonyms | Champacol; Guaiac alcohol |
| SMILES | C[C@@H]1C2=C([C@H](CC[C@@H](C(C)(O)C)C2)C)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.