Fig. 1 · Structure

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Guanethidine sesquisulfate

Antihypertensive Agent

Guanethidine sesquisulfate is an antihypertensive agent that functions primarily as an adrenergic neuron-blocking compound. It selectively enters noradrenergic nerve terminals via the neuronal amine carrier, leading to a reduction in norepinephrine release. This mechanism results in lowered sympathetic outflow, making it valuable in the study of blood pressure regulation and autonomic nervous system functions.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 60-02-6
Applications Antihypertensive Agent
Formula C10H22N4.1/2H2O4S
Molecular Weight 247.34
SMILES
O=S(O)(O)=O.N=C(NCCN1CCCCCCC1)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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