Fig. 1 · Structure
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Guanethidine sulfate
Antihypertensive Agent
Guanethidine sulfate is an adrenergic neuron blocking agent primarily utilized as an antihypertensive agent. It exerts its pharmacological effects by entering noradrenergic nerve terminals via the neuronal amine carrier, ultimately leading to the inhibition of norepinephrine release. This compound is widely used in research settings to study adrenergic signaling and cardiovascular pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 645-43-2 |
| Applications | Antihypertensive Agent |
| Formula | C10H24N4O4S |
| Molecular Weight | 296.39 |
| Synonyms | Guanethidine monosulfate |
| SMILES | NC(NCCN1CCCCCCC1)=N.O=S(O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.