Fig. 1 · Structure
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Guanidine hydrochloride
Chaotrope Agent
Guanidine hydrochloride acts as a potent chaotrope and is widely recognized as a strong denaturant of proteins. By disrupting hydrogen bonds and hydrophobic interactions, it facilitates protein unfolding, which is essential in various biochemical and biophysical studies. This reagent is commonly utilized in protein refolding experiments, purification processes, and to investigate protein structure-function relationships in research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 50-01-1 |
| Applications | Chaotrope Agent |
| Formula | CH6ClN3 |
| Molecular Weight | 95.53 |
| Synonyms | Guanidinium chloride; Aminoformamidine hydrochloride |
| SMILES | NC(N)=N.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.