Fig. 1 · Structure
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Guanidinoethyl sulfonate
Taurine Depletor
Guanidinoethyl sulfonate is a taurine transport inhibitor that functions as a competitive antagonist of glycine receptors (GlyR), with an IC50 of 565 μM. This compound possesses both weak agonistic and antagonistic properties on GABAA receptors. By inhibiting taurine transmembrane transport and blocking glycine-mediated chloride influx, it may help to regulate brain pH—an essential factor in neuroprotection. Guanidinoethyl sulfonate is valuable for research focused on neuroprotection in ischemic brain injury.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 543-18-0 |
| Applications | Taurine Depletor |
| Formula | C3H9N3O3S |
| Molecular Weight | 167.19 |
| Synonyms | Taurocyamine |
| SMILES | N=C(NCCS(=O)(O)=O)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.