Fig. 1 · Structure
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Guanosine 5'-diphosphate sodium, 96% (HPLC)
Iron Mobilizer
Guanosine 5'-diphosphate sodium is an iron mobilizer that functions by inhibiting the interaction between hepcidin and ferroportin (FPN). This nucleoside diphosphate also modulates the IL-6/Stat-3 signaling pathway, demonstrating key biological activity in inflammation-related disorders. Research has shown that Guanosine 5'-diphosphate sodium can ameliorate Turpentine-induced anemia of inflammation in murine models when administered in conjunction with FeSO4. It serves as a valuable reagent for studying iron mobilization and related inflammatory responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 43139-22-6 |
| Applications | Iron Mobilizer |
| Formula | C10H14N5NaO11P2 |
| Molecular Weight | 465.18 |
| Synonyms | GDP sodium; Type I; 96% (HPLC) |
| SMILES | O=P(OP(O)(O[Na])=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.