GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A16238
Formula
C17H13N3O
Molecular Weight
275.31
CAS Number
504433-23-2
SMILES
O=C1/C(C2=NC=CC=C2N1)=C\C3=CN(C)C4=C3C=CC=C4
Synonyms
GW-441756, GW441756
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
25 mg/mL (90.81 mM)
Water
Insoluble
Ethanol
Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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