GW 441756

Catalog No.: A16238

TrkA inhibitor

GW 441756

GW 441756 Chemical Structure

CAS NO. 504433-23-2

GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.

Availability: In stock

Package Price Qty
10 mg
$80.00
50 mg
$280.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.
Targets
TrkA CDK2 C-Raf-1
2 nM>7 μM>12 μM
In vitro DMSO 25 mg/mL (90.81 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.32 mL 181.61 mL 363.23 mL
0.5 mM 7.26 mL 36.32 mL 72.65 mL
1 mM 3.63 mL 18.16 mL 36.32 mL
5 mM 0.73 mL 3.63 mL 7.26 mL

*The above data is based on the productmolecular weight 275.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16238
Actions Inhibitor
CAS No. 504433-23-2
Formula C17H13N3O
M. Wt 275.31
Purity >98%
Synonyms GW-441756, GW441756
SMILES O=C1/C(C2=NC=CC=C2N1)=C\C3=CN(C)C4=C3C=CC=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy GW 441756 | GW 441756 Supplier | purchase | cost | manufacturer | order | distributor | buy 504433-23-2| 504433-23-2 Supplier | purchase 504433-23-2 | 504433-23-2 cost | 504433-23-2 manufacturer | order 504433-23-2 | 504433-23-2 distributor
Rewards