GW 441756

Catalog No.: A16238

TrkA inhibitor

GW 441756

GW 441756 Chemical Structure

CAS NO. 504433-23-2

GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.

Availability: In stock

Package Price Qty
10 mg
$80.00
50 mg
$280.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.
Targets
TrkA CDK2 C-Raf-1
2 nM>7 μM>12 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.32 mL 181.61 mL 363.23 mL
0.5 mM 7.26 mL 36.32 mL 72.65 mL
1 mM 3.63 mL 18.16 mL 36.32 mL
5 mM 0.73 mL 3.63 mL 7.26 mL

*The above data is based on the productmolecular weight 275.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16238
Actions Inhibitor
M. Wt 275.31
Formula C17H13N3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 504433-23-2
Synonyms GW-441756, GW441756
SMILES O=C1/C(C2=NC=CC=C2N1)=C\C3=CN(C)C4=C3C=CC=C4

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