Fig. 1 · Structure
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GW 610
Antitumor Agent
GW 610 (NSC 721648) is a potent aryl hydrocarbon receptor (AhR) ligand with a binding affinity (Ki) of 6.8 nM. This compound effectively induces cytochrome P450 1A1 (CYP1A1) expression in MCF-7 breast cancer cells. GW 610 exhibits significant anticancer activity, demonstrating selectivity against various cancer cell lines, including those from lung, colon, and breast origins, making it a valuable tool for cancer research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 872726-44-8 |
| Applications | Antitumor Agent |
| Formula | C15H12FNO2S |
| Molecular Weight | 289.32 |
| Synonyms | NSC 721648 |
| SMILES | FC1=CC=C(SC(C2=CC=C(OC)C(OC)=C2)=N3)C3=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.