GW-803430

Catalog No.: A61605
MCH R1 Antagonist
GW-803430 is a potent and selective antagonist of the melanin-concentrating hormone receptor 1 (MCH R1), exhibiting a pIC50 of 9.3. This compound demonstrates significant biological activity by inhibiting MCH R1, which plays a critical role in regulating energy balance and appetite. GW-803430 is primarily utilized in research applications focusing on obesity and metabolic disorders, providing insight into the therapeutic potential for weight management strategies.
Grouped product items
Size Price Stock Qty
1mg
$45.00
In stock
2mg
$65.00
In stock
5mg
$115.00
In stock
10mg
$200.00
In stock
25mg
$405.00
In stock
50mg
$605.00
In stock
100mg
$800.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGW-803430 is a potent and selective antagonist of the melanin-concentrating hormone receptor 1 (MCH R1), exhibiting a pIC50 of 9.3. This compound demonstrates significant biological activity by inhibiting MCH R1, which plays a critical role in regulating energy balance and appetite. GW-803430 is primarily utilized in research applications focusing on obesity and metabolic disorders, providing insight into the therapeutic potential for weight management strategies.
Product Information
Catalog NumA61605
FormulaC25H24ClN3O3S
Molecular Weight481.99
CAS Number515141-51-2
SMILESO=C1C2=C(C=C(C3=CC=C(Cl)C=C3)S2)N=CN1C4=CC=C(OCCN5CCCC5)C(OC)=C4
SynonymsGW-3430
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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