GW-870086

Catalog No.: A18343

Glucocorticoid receptor agonist

GW-870086

GW-870086 Chemical Structure

CAS NO. 827319-43-7

GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$150.00
50 mg
$450.00
100 mg
$850.00
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Biological Activity

GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.87 mL 89.34 mL 178.69 mL
0.5 mM 3.57 mL 17.87 mL 35.74 mL
1 mM 1.79 mL 8.93 mL 17.87 mL
5 mM 0.36 mL 1.79 mL 3.57 mL

*The above data is based on the productmolecular weight 559.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18343
Actions Agonist
M. Wt 559.64
Formula C31H39F2NO6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 827319-43-7
Synonyms GW 870086 , GW870086
SMILES C[[email protected]@]12[[email protected]](C(OCC#N)=O)(OC(C3C(C)(C)C3(C)C)=O)[[email protected]](C)C[[email protected]@]1([H])[[email protected]]4([H])C[[email protected]](F)C5=CC(C=C[[email protected]]5(C)[[email protected]@]4(F)[[email protected]@H](O)C2)=O

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