GW2580-d6 is a deuterium-labeled variant of GW2580, a selective and orally bioavailable inhibitor of c-Fms kinase. It effectively inhibits human c-Fms kinase in vitro at a concentration of 0.06 μM by acting as a competitive inhibitor of ATP binding, thereby disrupting colony-stimulating factor-1 (CSF-1) signaling pathways. This reagent is valuable for studying signaling processes mediated by c-Fms in various biological contexts and provides insights into macrophage biology and inflammatory responses.
GW2580-d6 is a deuterium-labeled variant of GW2580, a selective and orally bioavailable inhibitor of c-Fms kinase. It effectively inhibits human c-Fms kinase in vitro at a concentration of 0.06 μM by acting as a competitive inhibitor of ATP binding, thereby disrupting colony-stimulating factor-1 (CSF-1) signaling pathways. This reagent is valuable for studying signaling processes mediated by c-Fms in various biological contexts and provides insights into macrophage biology and inflammatory responses.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
