Catalog No.: A11959
CSF-1R inhibitor
GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase.
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GW2580 25mg
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GW2580 50mg
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GW2580 100mg
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GW2580 200mg
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GW2580 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's GW2580 has been cited by 2 publications
  • Ravikanth Maddipati, .et al. , bioRxiv, 2021, February 01
  • Liu M, .et al. , Nat Immunol, 2019, Jan 21 PMID: 30664738
  • Biological Activity
    Discription GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase.
    Product Information
    Catalog Num A11959
    Formula C20H22N4O3
    Molecular Weight 366.41
    CAS Number 870483-87-7
    Synonyms GW 2580, GW-2580

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 48 mg/mL (131 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.29 mL 136.46 mL 272.92 mL
    0.5 mM 5.46 mL 27.29 mL 54.58 mL
    1 mM 2.73 mL 13.65 mL 27.29 mL
    5 mM 0.55 mL 2.73 mL 5.46 mL
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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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