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CSF-1R inhibitor

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Catalog No. A11959

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GW2580 25mg A11959-25

Regular Price: $40.00

Special Price: $36.00

GW2580 50mg A11959-50

Regular Price: $70.00

Special Price: $63.00

GW2580 100mg A11959-100

Regular Price: $90.00

Special Price: $81.00

GW2580 200mg A11959-200

Regular Price: $140.00

Special Price: $126.00

GW2580 10mM * 1mL in DMSO A11959-10mM-D

Regular Price: $70.00

Special Price: $63.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase.


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Publications citing Adooq Products
GW2580 Citations (1)
  • Liu M, .et al. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47???mediated -don-t-eat-me- signal, Nat Immunol, 2019, Jan 21 PMID: 30664738

Chemical Information

Catalog Num A11959
Actions Inhibitor
M. Wt 366.41
Formula C??H??N?O?
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 870483-87-7
Synonyms GW 2580, GW-2580

Biological Activity

GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase.


Solubility (25°C) * In vitro DMSO 48 mg/mL (131 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.29 mL 136.46 mL 272.92mL
0.5 mM 5.46 mL 27.29 mL 54.58 mL
1 mM 2.73 mL 13.65 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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