Fig. 1 · Structure

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GW273297X

Cat. No. A69829 CAS 1713317-28-2

CYP27A1 Inhibitor

GW273297X is a selective inhibitor of CYP27A1, a key enzyme involved in cholesterol metabolism. This compound effectively reduces the concentration of 27-hydroxycholesterol (27HC) in E0771 tumor models in APOE3 mice. GW273297X serves as a valuable tool for investigating the role of CYP27A1 in breast cancer research and its potential impact on tumor progression and metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1713317-28-2
Applications CYP27A1 Inhibitor
Formula C29H48O3
Molecular Weight 444.69
Synonyms G297X
SMILES
C[C@@]12[C@]3([H])[C@]([C@@H](C[C@]1([H])CC(OC)(CC2)OC)O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)[C@H](C)CCCCC#C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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