Fig. 1 · Structure
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GW6340
LXR Agonist
GW6340 is an intestinal-specific liver X receptor (LXR) agonist that enhances macrophage reverse cholesterol transport (mRCT). This compound serves as a valuable tool in studying lipid metabolism and cardiovascular diseases. Its ability to modulate cholesterol homeostasis makes it a suitable candidate for research in atherosclerosis and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 405910-78-3 |
| Applications | LXR Agonist |
| Formula | C33H32ClF3N2O2 |
| Molecular Weight | 581.07 |
| SMILES | O=C(CC1=CC(OCCCN(CC(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC=CC(C(F)(F)F)=C4Cl)=CC=C1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.