Fig. 1 · Structure
Documents & Downloads
GW814408X
AURKC Inhibitor
GW814408X is a selective inhibitor of AURKC, a kinase critical for cell cycle progression, checkpoint regulation, and mitosis. This compound demonstrates cell line-dependent toxicity, particularly exhibiting cytotoxic effects in HeLa cells. GW814408X also functions as a protein kinase inhibitor that may interfere with ATP-dependent and -independent luciferases, making it a valuable tool for Fluc reporter assays and related biological research applications.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 886599-05-9 |
| Applications | AURKC Inhibitor |
| Formula | C19H16N6O |
| Molecular Weight | 344.37 |
| SMILES | COC1=CC(C2=CNC3=C2N=CN=C3N/N=C/C4=CC=NC=C4)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.