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GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains. GW841819X was a single enantiomer but of undefined chirality at the 4-position of the benzodiazepine ring 3.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.49 mL | 102.47 mL | 204.94 mL |
| 0.5 mM | 4.1 mL | 20.49 mL | 40.99 mL |
| 1 mM | 2.05 mL | 10.25 mL | 20.49 mL |
| 5 mM | 0.41 mL | 2.05 mL | 4.1 mL |
*The above data is based on the productmolecular weight 487.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16367 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 487.94 |
| Formula | C26H22ClN5O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 146135-18-4 |
| Synonyms | GW-841819X, GW 841819X |
| SMILES | ClC(C=C1)=CC=C1C2=N[[email protected]@H](NC(OCC3=CC=CC=C3)=O)C4=NN=C(C)N4C5=CC=C(OC)C=C52 |
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